Kidney diseases

 Definition

The rare kidney diseases can be dismembered into three groups of diseases:

The congenital anomalies of the renal development
Monogenetic kidney disease  identified
The nephrotic syndromes.

These diseases have in common a rare impact , a phenotypic presentation varies according to the age, a risk of evolution toward the renal insufficiency, an HTA, possible repercussions on the growth among children.

All of these rare diseases require a suitable support and early, pledge of an evolution slowed down as well as a prolonged monitoring and follow-up.

Statestics

In France, nearly 5% of adult population, or three million people, suffer from a disease of kidney, 9500 begin a dialysis treatment each year, 37500 are in course of dialysis and 33000 have benefited from a kidney transplant. At the scale of the planet, it is estimated that 400 to 600 million people are reached.
Despite this frequency, there is a real ignorance of these diseases on the part of the French, very worried about the cardiac risk or cancer but largely ignorant of everything that affects the kidneys. Until the day when, without warning, the disease strikes, them or one of their relatives.

 March 8, the World Kidney Day

The objective of the World kidney Day, On March 8, is the special day to make better known these pathologies in order that they are taken by and supported earlier when they are still accessible to a simple treatment. This world kidney day, placed in France under the aegis and support of Kidney Foundation, should give rise to hundreds of events in 112 countries on six continents.

Diabetes and hypertension

The classical kidney disease are inflammations or infections of the kidneys, urinary tract obstructions or even genetic diseases such as polycystic kidney. But the diabetes and hypertension, which exploded the number of cases in all countries, including those in process of development, are now the largest suppliers of chronic renal insufficiency.

Diabetes and hypertension alter little by little the micro-circulation of the kidney, without symptoms, without pain and without specific disorders, until the moment when the latter is exhausted, can no longer ensure its functions for purification of blood. It is the renal insufficiency, with its attendant disorders, fatigue associated with anemia, weight loss, digestive disorders: anorexia, nausea, vomiting, diarrhea, digestive hemorrhage, neurological disorders, fatigue of calves, paraesthesia (tingling in the legs)

Few symptoms

In addition, sufferers have an increased risk of myocardial infarction, heart or stroke failure  accident cerebral  vascular.
The renal disease does not entail long these few symptoms, but it is easy to detect by the exams very simple, such as the assay of albumin in the urine and creatinine in blood. These determinations must be made in priority in patients with diabetes and hypertension. An early detection and treatment can often prevent the progression to renal failure, dialysis or transplantation.

References

Kidney disease: translated